What Is Orlos 60mg?

Orlos is a weight-management medicine containing 60mg of orlistat per capsule.

Orlistat works differently from appetite-regulating treatments such as GLP-1 injections. Instead of reducing hunger directly, it acts inside the gastrointestinal system and prevents some dietary fat from being broken down and absorbed.

A portion of the fat eaten with meals therefore passes through the digestive system rather than being absorbed as calories.

Orlos should be combined with a nutritionally balanced, calorie-controlled and lower-fat diet.

For additional weight-management options, explore MySlimCare Weight Loss Treatments.

What Is the Active Ingredient in Orlos?

The active ingredient is orlistat.

Orlistat belongs to a group of medicines known as lipase inhibitors.

Lipase enzymes in the stomach and pancreas normally break dietary fats into smaller components that can be absorbed by the body.

Orlistat reduces the activity of these enzymes.

As a result, some of the fat consumed during a meal remains undigested and leaves the body through the bowel.

The European Medicines Agency describes the same mechanism for authorised 60mg orlistat medicines.

How Does Orlos Work for Weight Loss?

Orlos works directly on dietary fat.

When taken with an appropriate meal, orlistat inhibits digestive lipases. This means that less of the fat contained in food is absorbed.

At the 60mg strength, authorised orlistat products reduce absorption of approximately a quarter of consumed dietary fat.

This reduces the number of calories absorbed from fat and can help support gradual weight loss when combined with a calorie deficit and regular physical activity.

Orlos does not:

• burn existing body fat directly;
• increase metabolism dramatically;
• suppress appetite in the same way as GLP-1 medicines; or
• replace healthy eating and exercise.

It is best considered as an additional tool within a broader weight-management programme.

Who Can Use Orlos 60mg?

Lower-strength 60mg orlistat medicines are intended for overweight adults with a BMI of 28kg/m² or above, in combination with a reduced-calorie, lower-fat diet.

BMI is calculated using your weight and height.

Treatment suitability can also depend on:

• medical history;
• existing health conditions;
• medicines you currently take;
• previous weight-management treatments;
• pregnancy or breastfeeding status; and
• other individual risk factors.

If you are unsure whether Orlos is appropriate, start your MySlimCare consultation.

How Should I Take Orlos?

Orlos is taken with meals that contain fat.

The usual approach for 60mg orlistat products is:

One 60mg capsule immediately before, during or within one hour after each main meal containing fat.

It can therefore be taken up to three times daily.

If you skip a meal or eat a meal containing no fat, you should normally skip that dose.

Do not take additional capsules to compensate.

How Many Orlos Capsules Can I Take Per Day?

The usual maximum is three 60mg capsules in a 24-hour period, one with each main fat-containing meal.

Taking more than the recommended dose does not improve weight loss and may increase the likelihood of adverse effects.

Always follow the instructions supplied with your specific Orlos pack.

What Should I Eat While Taking Orlos?

Diet is particularly important when using orlistat.

Your daily food intake should be:

• calorie controlled;
• nutritionally balanced;
• relatively low in fat; and
• spread sensibly across your main meals.

Try to include:

• vegetables;
• fruit;
• whole grains;
• lean proteins;
• pulses and legumes; and
• moderate quantities of healthier fats.

Very high-fat meals increase the amount of unabsorbed fat entering the bowel and therefore increase the risk of gastrointestinal side effects.

Visit MySlimCare Weight Management Advice for more guidance.

What Foods Should I Avoid While Taking Orlos?

You do not need to eliminate fat completely, but very fatty foods should be limited.

Examples that may make digestive effects worse include:

• deep-fried foods;
• fatty takeaway meals;
• high-fat processed meats;
• large amounts of cheese;
• cream-based sauces;
• pastries and rich desserts; and
• meals containing unusually large amounts of oil.

Spreading your daily fat intake evenly between meals can make Orlos easier to tolerate.

Why Does Orlos Cause Oily Stools?

Orlos prevents some dietary fat from being absorbed.

That unabsorbed fat then passes through the bowel.

As a result, some people experience:

• oily stools;
• fatty or oily spotting;
• more frequent bowel movements;
• bowel urgency;
• flatulence with discharge; or
• loose stools.

These effects are closely linked to the amount of fat consumed.

A lower-fat diet can significantly reduce them.

How Long Does Orlos Take to Work?

Orlistat begins reducing fat absorption shortly after treatment starts.

However, visible weight loss develops progressively.

Your result depends on:

• overall calorie intake;
• dietary fat;
• consistency with treatment;
• physical activity;
• starting weight; and
• individual biology.

Weight-management progress should therefore be assessed over weeks and months, not just days.

How Long Can I Take Orlos?

Lower-dose orlistat treatment should not simply be continued indefinitely without review.

If you are not losing weight despite following the recommended diet and using the medicine correctly, speak with a healthcare professional.

Treatment may need to be stopped or another weight-management strategy considered.

For longer-term or prescription-strength weight-management options, explore MySlimCare treatments.

What Happens If I Forget a Dose?

If you forget to take Orlos with a meal and more than one hour has passed, you would normally skip that dose.

Take the next dose with your next main meal containing fat.

Do not double the dose.

Do I Need a Vitamin Supplement With Orlos?

Orlistat can reduce absorption of fat-soluble vitamins.

These include:

• vitamin A;
• vitamin D;
• vitamin E; and
• vitamin K.

Depending on your diet and treatment duration, a healthcare professional may recommend a multivitamin.

If a supplement is used, it is generally taken separately from orlistat so absorption is less likely to be affected.

Always follow professional advice.

What Are the Common Side Effects of Orlos?

The most common effects relate to the digestive system.

They can include:

• oily spotting;
• oily or fatty stools;
• flatulence with oily discharge;
• bowel urgency;
• increased bowel movements;
• soft stools;
• abdominal discomfort; and
• difficulty controlling bowel movements.

These effects are more likely after high-fat meals.

Many people find that dietary adjustments make treatment easier to tolerate.

Are There Serious Side Effects?

Although serious adverse effects are less common, seek medical advice if you experience severe, persistent or unusual symptoms.

Orlistat medicines have been monitored for rare reports involving problems such as liver injury and other significant adverse reactions. EMA has reviewed orlistat’s safety and concluded that the benefits of authorised products continued to outweigh the risks when used appropriately.

Always read the current leaflet supplied with your medicine.

Who Should Not Take Orlos?

Orlos may not be suitable if you:

• are allergic to orlistat or another ingredient;
• have chronic malabsorption problems;
• have cholestasis;
• are pregnant;
• are breastfeeding, depending on professional advice; or
• take medicines that interact significantly with orlistat.

Your complete medication and medical history should be considered before starting treatment.

Does Orlos Interact With Other Medicines?

Orlistat can interfere with certain medicines or alter their absorption.

Medicines that may require special consideration include:

• ciclosporin;
• anticoagulants such as warfarin;
• levothyroxine;
• some anti-epileptic medicines;
• diabetes medicines; and
• certain other treatments.

This list is not exhaustive.

Always tell your healthcare professional about all prescription medicines, over-the-counter products and supplements you use.

Can I Drink Alcohol While Taking Orlos?

There is no major direct interaction between orlistat and alcohol.

However, alcohol can contain significant calories and may make achieving a calorie deficit more difficult.

Alcohol may also make it easier to choose high-fat or high-calorie foods.

Reducing alcohol can therefore support your broader weight-management goals.

Can I Take Orlos During Pregnancy?

Weight-loss treatment is not normally recommended during pregnancy.

If you:

• are pregnant;
• think you might be pregnant;
• are trying to conceive; or
• are breastfeeding,

speak to an appropriate healthcare professional before using Orlos.

Can I Exercise While Taking Orlos?

Yes.

Orlos is designed to support weight loss alongside diet and lifestyle changes, and regular physical activity can improve weight-management outcomes.

Your exercise programme should be appropriate for your individual fitness and health circumstances.

If you have existing medical conditions or have not exercised regularly before, consider seeking professional advice before beginning an intensive programme.

Orlos vs Alli

Orlos and Alli both contain 60mg of orlistat per capsule.

Their mechanism is therefore fundamentally the same.

Differences may include:

• brand;
• manufacturer;
• packaging;
• inactive ingredients;
• availability; and
• price.

Both are lower-strength orlistat products intended for overweight adults who meet the appropriate eligibility criteria.

View Alli Weight Loss Capsules

Orlos 60mg vs Orlistat 120mg

The main difference is dose strength.

Orlos

Contains 60mg orlistat per capsule.

Prescription Orlistat

Common prescription formulations contain 120mg orlistat per capsule.

Higher strength does not automatically mean it is the better option for every person.

Treatment choice depends on BMI, individual circumstances and applicable prescribing requirements.

View Orlistat 120mg

Orlos vs Xenical

Xenical contains 120mg orlistat per capsule, while Orlos contains 60mg.

Both reduce dietary fat absorption by inhibiting gastrointestinal lipases, but their strength and supply conditions differ.

Xenical is the established branded prescription-strength orlistat medicine authorised across the EU.

View Xenical 120mg

Orlos vs Weight Loss Injections

Orlos works differently from injectable weight-management medicines.

Orlos

Works inside the digestive system and reduces absorption of dietary fat.

GLP-1 and Related Weight Loss Injections

Treatments such as tirzepatide and authorised semaglutide products act primarily on hormonal pathways involved in appetite, satiety and food intake.

Some people may prefer an oral treatment, whereas others may be eligible for injectable options.

The appropriate choice depends on individual medical circumstances